4-Benzyl-6-bromo-2-(4-methoxyphenyl)-4H-imidazo[4,5-b]pyridine monohydrate
نویسندگان
چکیده
The imidazopyridine fused ring in the title compound, C(20)H(16)BrN(3)O·H(2)O, is coplanar with the aromatic ring at the 2-position [dihedral angle = 5.2 (1)°]. In the five-membered imidazo portion, the C-N bond whose C atom is also connected to the pyridine N atom has predominantly double-bond character [1.334 (2) Å] whereas the C-N bond whose atom is connected to the pyridine C atom has predominantly single-bond character [1.371 (2) Å]. The water mol-ecule engages in hydrogen bonding with the latter N atom; it is also connected to a symmetry-related water mol-ecule, generating a linear chain structure.
منابع مشابه
4-Benzyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine
The imidazopyridine fused ring in the title compound, C(19)H(14)BrN(3), is almost coplanar with the phenyl ring at the 2-position of the five-membered ring [dihedral angle = 2.4 (1). The crystal structure features short Br⋯Br contacts [3.562 (1) Å].
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There are two crystallographically independent mol-ecules in the asymmetric unit of the title compound, C(22)H(17)BrN(6). The dihedral angles between the imidazo[4,5-b]pyridine mean plane and the phenyl rings are 20.4 (2) and 24.0 (2)° in the two mol-ecules. The orientation of triazoles compared to the imidazo[4,5-b]pyridine system is almost the same in both mol-ecules, with dihedral angles of ...
متن کامل4-Allyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine monohydrate
In the mol-ecule of the title compound, C(15)H(12)BrN(3)·H(2)O, the phenyl ring is coplanar with the imidazopyridine ring system [dihedral angle = 0.4 (1)°]. The water mol-ecule is disordered over two positions with occupancies of 0.58 (1) and 0.42 (1), and it is linked to the main mol-ecule via an O-H⋯N hydrogen bond.
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1-alkyl aryl-5-amino-4-(cyanoformimidoyl)imidazoles 4 were reacted with malononitrile and 2-amino-1,1,3-propenetricarbonitrile under mild experimental conditions, which led to 5-amino-3-(substituted benzyl)-6,7-dicyano-3H-imidazo[4,5-b]pyridines 5 and 6,8-diamino-3-(4-substituted benzyl)-3H-imidazo[4,5-b]-1,8-naphthyridine-7,9-dicarbonitrile 6, respectively, when the reaction was carried out in...
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In the title compound, C12H8BrN3O, the 4-bromo-phenol ring is coplanar with the planar imidazo[4,5-b]pyridine moiety (r.m.s deviation = 0.015 Å), making a dihedral angle of 1.8 (2)°. There is an intra-molecular O-H⋯N hydrogen bond forming an S(6) ring motif. In the crystal, mol-ecules are linked via N-H⋯N and O-H⋯Br hydrogen bonds, forming undulating sheets parallel to (10-2). The sheets are li...
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